Abstract: With the development of medical education reform, organ-based and system-centered medical integration courses and problem-based learning (PBL) teaching methods have been paying more and more attention to clinical teaching. PBL is an important product and milestone in the reform and development of clinical medicine education in the United States. Its core content is problem-based learning. Its goal is to cultivate students' self-learning ability, practice thinking ability and innovation ability. The author introduced the development of American clinical medicine education reform and PBL teaching method in detail, and the advanced experience of clinical medicine education of David Geffen School of Medicine, University of California, Los Angeles, especially PBL teaching method. Geriatric medicine has not been paid much attention in clinical teaching for a long time in China. The author brought the enlightenments to the clinical education of Geriatrics in China:to strengthen the clinical education of Geriatrics, optimize the curriculum and introduce PBL in clinical teaching, increase the guiding role of teachers, introduce humanities education and enhance students self-learning ability, problem-exploring, problem-solving ability and innovation ability. Meanwhile it introduces the humanistic education to the specialized courses in order to cultivate outstanding geriatrician.