农村老年人多重慢病与运动认知风险综合征的相关性研究

代晨; 张燕; 张静雅; 王青; 娄旭; 陈任; 沈国栋

doi:10.16766/j.cnki.issn.1674-4152.003359

农村老年人多重慢病与运动认知风险综合征的相关性研究

doi: 10.16766/j.cnki.issn.1674-4152.003359

代晨¹,
张燕^1, ,,
张静雅¹,
王青¹,
娄旭²,
陈任¹,
沈国栋³

1.
安徽医科大学卫生管理学院，安徽合肥 230032
2.
安徽体育运动职业技术学院，安徽合肥 230052
3.
中国科学技术大学附属第一医院老年医学科，安徽合肥 230051

基金项目:

国家自然科学基金青年基金项目 72004003

安徽省优秀科研创新团队项目 2023AH010036

安徽省教育厅高校科研重点项目 2022AH053118

详细信息

通讯作者:
张燕，E-mail：zhangymail@ahmu.edu.cn

中图分类号: R592
计量
- 文章访问数: 132
- HTML全文浏览量: 30
- PDF下载量: 29
- 被引次数: 0
出版历程
- 收稿日期: 2023-10-30
- 网络出版日期: 2024-03-27

A study on the correlation between multimorbidity and motoric cognitive risk syndrome in rural older adults

1.
School of Health Service Management, Anhui Medical University, Hefei, Anhui 230032, China

摘要

摘要: 目的本研究旨在调查安徽省农村老年人多重慢病与运动认知风险综合征(MCR)之间的横断面关系，探索慢性疾病数量与MCR之间的关联，以期为在农村的特定社会情境下，制定预防MCR的策略和措施提供依据。方法采用方便抽样方法选取安徽省六安和阜阳两地农村地区的652名老年人进行调查，开展多重慢病与MCR之间的相关性研究。其中慢性疾病状态以参与者自我报告的形式进行记录，MCR通过结合步态缓慢和主观认知下降进行评估。采用logistic回归分析研究多重慢病与MCR之间的关系。结果患有任何一种慢性疾病的老年人更可能患有MCR(OR=2.926，95% CI：1.256~6.816，P=0.013)。多重慢病的数量与MCR显著相关，其中患有3种慢性疾病的老年人患MCR的风险最高(OR=4.946，95% CI：1.811~13.506，P=0.002)。Logistic回归分析显示，高血压+抑郁症(OR=2.433，95% CI：1.294~4.573，P=0.006)和高血压+高脂血症+抑郁症(OR=4.632，95% CI：1.978~10.848，P<0.001)两组多重慢病模式的老年人更容易患有MCR。结论在安徽省农村老年人中，多重慢病与MCR具有相关性，患有MCR的概率随着慢性疾病数量的累积而增加。
- 多重慢病 /
- 运动认知风险综合征 /
- 老年人 /
- 农村
Abstract: Objective To investigate the cross-sectional relationship between multimorbidity and motoric cognitive risk syndrome (MCR) among older adults in Anhui province, China. To explore the association between the number of chronic diseases and MCR in order to provide a basis for the development of strategies and measures to prevent MCR in rural areas. Methods A cross-sectional study was conducted among 652 older adults in rural areas of Lu' an and Fuyang City, Anhui Province, China, participants self-reported their chronic disease status. MCR was assessed by combining slow gait with subjective cognitive decline, and logistic regression was used to analyze the relationship between multimorbidity and MCR. Results Older adults with chronic disease had a higher likelihood of experiencing MCR (OR=2.926, 95% CI: 1.256-6.816, P=0.013). Further, the presence of three chronic diseases in older adults was associated with the highest risk of MCR (OR=4.946, 95% CI: 1.811-13.506, P=0.002). Logistic regression analysis showed that older adults with specific multimorbidity patterns, such as hypertension+depression (OR=2.433, 95% CI: 1.294-4.573, P=0.006) and hypertension+hyperlipidemia+depression (OR=4.632, 95% CI: 1.978-10.848, P<0.001), were more prone to developing MCR. Conclusion MCR is associated with multimorbidity among older adults in rural Anhui province, China.
- Multimorbidity /
- Motoric cognitive risk syndrome /
- The aged /
- Rural

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图 1 研究对象的多重慢病模式

Figure 1. Multimorbidity patterns of the participants

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表 1 623名研究对象的社会人口学特征

Table 1. Sociodemographic characteristics of 623 participants

项目	人数	百分比(%)
性别
男性	284	45.6
女性	339	54.4
城市
六安	197	31.6
阜阳	426	68.4
教育程度
文盲	381	61.2
非文盲	242	38.8
社会隔离
社会隔离	260	41.7
非社会隔离	363	58.3
衰弱状态
衰弱	283	45.4
非衰弱	340	54.6
吸烟者
是	116	18.6
否	507	81.4
饮酒者
是	134	21.5
否	489	78.5
规律运动
是	455	73.0
否	168	27.0
多重慢病
是	282	45.3
否	341	54.7
MCR
是	105	16.9
否	518	83.1

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表 2 慢性病状况与MCR之间的相关性

Table 2. The associations between chronic diseases status and MCR

变量	MCR
变量	OR值	95% CI	P值
慢性病
否	参照组
是	2.926	1.256~6.816	0.013
慢性病数量^a
无慢性病	参照组
1种慢性病	2.211	0.898~5.445	0.084
2种慢性病	3.579	1.460~8.780	0.005
3种慢性病	4.946	1.811~13.506	0.002
4种慢性病	2.067	0.490~8.713	0.322
注：^aP_趋势=0.006。赋值方法如下，无慢性病=0，慢性病=1；无慢性病=0，有1种慢性病=1，有2种慢性病=2，有3种慢性病=3，有4种慢性病=4。

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表 3 多重慢病模式与MCR之间的相关性

Table 3. The associations between multimorbidity patterns and MCR

变量	MCR
变量	OR值	95% CI	P值
多重慢病
否	参照组
是	2.068	1.255~3.408	0.004
多重慢病模式
无多重慢病组	参照组
高血压+高脂血症	1.568	0.534~4.605	0.413
高血压+糖尿病	0.940	0.257~3.436	0.926
高血压+抑郁	2.433	1.294~4.573	0.006
高脂血症+抑郁	1.411	0.263~7.568	0.688
糖尿病+抑郁	5.079	0.991~26.028	0.051
高血压+高脂血症+糖尿病	1.315	0.335~5.157	0.694
高血压+高脂血症+抑郁	4.632	1.978~10.848	<0.001
高血压+糖尿病+抑郁	1.692	0.495~5.781	0.401
高血压+高脂血症+糖尿病+抑郁	1.192	0.345~4.119	0.781
注：高脂血症+糖尿病多重慢病组合因人数较少(n=1)剔除。赋值方法如下，是=1，否=0；多重慢病模式，无多重慢病=(0，0，0，0，0，0，0，0，0)，高血压+高脂血症=(1，0，0，0，0，0，0，0，0)，高血压+糖尿病=(0，1，0，0，0，0，0，0，0)，高血压+抑郁=(0，0，1，0，0，0，0，0，0)，高脂血症+抑郁=(0，0，0，1，0，0，0，0，0)，糖尿病+抑郁=(0，0，0，0，1，0，0，0，0)，高血压+高脂血症+糖尿病=(0，0，0，0，0，1，0，0，0)，高血压+高脂血症+抑郁=(0，0，0，0，0，0，1，0，0)，高血压+糖尿病+抑郁=(0，0，0，0，0，0，0，1，0)，高血压+高脂血症+糖尿病+抑郁=(0，0，0，0，0，0，0，0，1)。

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